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Itradus 200 mg (Itraconazole)


Active Ingredient (Generic Name): Itraconazole
Indication: Fungal infections
Manufacturer: Zydus Cadila Pharma
Packaging: 10 capsules in one strip
Strength: 200 mg

From: $104.00

Amount Price Price / Unit
Qty
Itradus 200 mg (Itraconazole) - 60-capsules 60 Capsules $104.00

$1.73

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Itradus 200 mg (Itraconazole) - 90-capsules 90 Capsules $129.00

$1.43

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Itradus 200 mg (Itraconazole) - 120-capsules 120 Capsules $164.00

$1.37

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Itradus 200 Mg, a prescription medication, contains itraconazole, an antifungal that treats various fungal infections, particularly in individuals with weakened immune systems. It works by inhibiting ergosterol synthesis in fungal cell membranes, disrupting cell integrity and causing cell death. The standard dosage is 200-400 mg daily, taken with a full meal to enhance absorption. Common side effects include nausea, vomiting, and diarrhea. Rare but severe side effects may include allergic reactions and liver problems. It is essential to be aware of precautions, contraindications, and overdose symptoms to ensure safe and effective treatment.

Main Points

Itradus 200 Mg is an antifungal medication containing itraconazole. It is used to treat fungal infections such as aspergillosis, blastomycosis, and histoplasmosis.

The typical adult dose of itraconazole ranges from 200 to 400 mg daily, divided into one or two doses depending on the type of infection.

Itraconazole works by inhibiting ergosterol synthesis in fungal cell membranes, disrupting cell integrity and causing cell death.

Common side effects of itraconazole include nausea, vomiting, diarrhea, stomach pain, and headaches. Rare but severe side effects may include allergic reactions and liver problems.

Itraconazole can interact with other medications, increasing the risk of adverse effects or reducing efficacy. Patients should disclose their medical conditions, medications, or supplements to their doctor.

What Is Itraconazole Used For?

Itraconazole is an antifungal medication used to treat various fungal infections, including aspergillosis, blastomycosis, and histoplasmosis. It is effective against fungal infections affecting the lungs, brain, and other organs. Itraconazole is commonly prescribed for fungal infections resistant to other antifungal medications. It is also used to treat fungal infections in people with weakened immune systems, such as those with cancer, HIV/AIDS, or undergoing chemotherapy. Additionally, itraconazole is used to prevent fungal infections in high-risk individuals, such as those undergoing bone marrow transplants.

How Does Itraconazole Work?

Itraconazole works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. This disrupts the integrity of the fungal cell, ultimately leading to its death.

The mechanism of action involves targeting the fungal cell membrane, causing it to weaken and eventually die. This is possible because ergosterol is essential for maintaining the structural integrity of the fungal cell membrane.

Itraconazole inhibits the enzyme lanosterol 14-alpha-demethylase, which is necessary for ergosterol synthesis. This inhibition leads to a decrease in ergosterol production, disrupting the fungal cell membrane. Disruption of the fungal cell membrane ultimately leads to the death of the fungal cell.

Itraconazole Side Effects

Itraconazole Side Effects

Itraconazole is generally well-tolerated, but it can cause side effects. Common side effects of Itradus 200 mg include nausea, vomiting, diarrhea, stomach pain, and headaches. These side effects are usually mild and temporary. If they persist or worsen, consult your doctor.

Rare but severe side effects may occur, including allergic reactions, liver problems, and heart rhythm disturbances. If you experience symptoms like difficulty breathing, swelling, or rapid heartbeat, seek immediate medical attention. Itraconazole can interact with other medications, so inform your doctor about all medications you’re currently taking.

Weigh the benefits of itraconazole against the potential risks. If you have concerns or questions, discuss them with your doctor. They can help you make an informed decision and monitor you for adverse reactions during treatment.

Itraconazole Dosage Instructions

Itradus 200 mg Dosage Instructions:

The typical adult dose of Itradus 200 mg ranges from 200 to 400 mg daily, divided into one or two doses, depending on the specific fungal infection being treated. Your doctor will determine the optimal dosage for your condition.

To ensure effective treatment and minimize side effects, follow these dosage instructions carefully:

  • Take Itradus 200 mg with a full meal to enhance absorption.
  • Swallow the capsules whole; do not crush, chew, or open them.
  • If you miss a dose, take it as soon as possible unless it’s close to the time for your next scheduled dose.

Precautions and Contraindications

Before initiating treatment with Itraconazole 200 mg, disclose any medical conditions, medications, or supplements to your doctor to prevent potential interactions or complications. Itraconazole may exacerbate existing conditions or interact with certain medications.

Notify your doctor if you have a history of heart, liver, or kidney disease, as Itraconazole may worsen these conditions.

Itraconazole is contraindicated in patients with a known hypersensitivity to the active ingredient or its excipients. It is not recommended for patients with congestive heart failure, as it may increase the risk of heart failure.

Pregnant or breastfeeding women should consult their doctor before taking Itraconazole 200 mg, as its safety in these populations has not been established.

Itraconazole may cause dizziness. Avoid driving or operating heavy machinery until you know how the medication affects you.

Itraconazole Interactions With Medications

Itraconazole Interactions With Medications

Inform your doctor about all medications, including prescription, over-the-counter, and herbal supplements, as Itraconazole 200 mg can interact with a wide range of drugs, increasing the risk of adverse effects or reducing its efficacy.

Medications that may interact with Itraconazole 200 mg include:

  • Antacids, which reduce absorption of Itraconazole
  • Calcium channel blockers, used to treat high blood pressure, which may increase the risk of heart problems
  • Warfarin, a blood thinner, which may increase the risk of bleeding

Disclose all medications you’re taking to your doctor to minimize the risk of interactions. Your doctor may adjust the dosage or recommend alternative medications to ensure safe and effective treatment.

Common Fungal Infections Treated

Fungal infections, including athlete’s foot, jock itch, and ringworm, can be treated with Itraconazole 200 mg.

Athlete’s foot, or tinea pedis, is a fungal infection affecting the feet, characterized by itching, burning, and cracking. Jock itch, or tinea cruris, affects the groin area, causing itching, redness, and ring-shaped rashes. Ringworm, or tinea corporis, is a fungal infection that causes circular patches on the skin, often accompanied by itching and redness.

Itraconazole 200 mg treats fungal infections by inhibiting fungal cell growth. It works by blocking ergosterol production, a critical component of fungal cell membranes. Without ergosterol, fungal cells cannot survive, and the infection begins to clear. By targeting fungal cells, Itraconazole 200 mg alleviates symptoms and promotes healing.

Itraconazole for Skin Infections

Itraconazole is an effective treatment for various skin infections, including cutaneous candidiasis and pityriasis versicolor, due to its antifungal properties.

Itraconazole has been proven to treat skin infections caused by fungi, such as Candida and Malassezia. It is commonly used to treat skin conditions like athlete’s foot, jock itch, and ringworm, which are caused by fungal infections. Additionally, itraconazole can be used to treat skin infections that are resistant to other antifungal treatments.

When using itraconazole for skin infections, it is essential to follow the dosage instructions carefully and complete the full treatment course. This helps ensure that the infection is fully cleared and reduces the risk of recurrence. Practicing good hygiene and keeping the affected area clean and dry also promotes healing and prevents the spread of infection.

Itraconazole for Nail Infections

Onychomycosis is a chronic fungal infection affecting the nails. Itraconazole is an effective treatment option that targets the infection by penetrating the nail plate.

Characterized by thickened, brittle, or discolored nails, onychomycosis requires prompt treatment to prevent complications. Itraconazole’s antifungal properties inhibit fungal cell growth, leading to their destruction.

When taken, itraconazole accumulates in the nail plate, providing a high concentration of the active ingredient at the site of infection. This targeted approach reduces the risk of relapse.

Doctors may prescribe itraconazole in combination with other treatments, such as nail debridement or topical creams, to provide comprehensive care. Understanding how itraconazole works enables individuals to take control of their nail health.

Itraconazole for Hair Infections

Itraconazole is a treatment option for hair infections. This antifungal medication combats fungal infections causing hair loss, promoting healthy hair growth. Taking Itradus 200 mg prevents further hair loss and addresses underlying fungal infections affecting hair.

Fungal Infection Treatment

Itraconazole is an antifungal medication used to treat fungal infections of the hair, including ringworm. It works by inhibiting fungal cell growth, leading to their death and the clearance of fungal infections, which promotes healthy hair growth.

Benefits of using itraconazole for fungal infection treatment include:

  • Rapid symptom relief: Itraconazole alleviates itching, redness, and swelling associated with fungal infections.
  • Broad-spectrum antifungal activity: Itraconazole is effective against various fungi, including Trichophyton, Epidermophyton, and Microsporum.
  • Convenient oral administration: Itraconazole is available in oral capsule form, making it easy to incorporate into daily routines.

Hair Loss Prevention

Itraconazole prevents hair loss by inhibiting fungal cell growth, promoting a healthy scalp environment. It targets underlying fungal infections, reducing shedding and breakage. The antifungal properties eliminate fungal infections, creating an environment conducive to healthy hair growth.

Itraconazole reduces inflammation, itchiness, and flaking associated with fungal infections, promoting a healthy scalp environment. This helps prevent hair loss and improves hair density and thickness as the infection clears. Completing the full treatment course as directed is crucial to ensure the infection is fully cleared and hair loss prevention is effective.

Overdose Symptoms and Treatment

Itraconazole overdose symptoms include nausea, vomiting, and abdominal pain. If you suspect an overdose, seek immediate medical attention.

Common Overdose Symptoms

Itraconazole overdose symptoms include:

Gastrointestinal disturbances: nausea, vomiting, diarrhea, dehydration, and electrolyte imbalance.

Common symptoms to watch for:

  • Cardiovascular issues: palpitations, rapid heart rate, low blood pressure
  • Neurological disturbances: headaches, dizziness, confusion
  • Hepatic dysfunction: elevated liver enzymes, indicating potential liver damage

Prompt medical attention is crucial, as these symptoms can worsen if left untreated. If an itraconazole overdose is suspected, seek immediate medical attention.

Treatment Options Available

Treatment for Itraconazole Overdose

If you have ingested an excessive amount of itraconazole, prompt medical attention is necessary to prevent further complications. The primary objective of treatment is to stabilize vital signs, manage symptoms, and prevent long-term damage.

Activated charcoal may be administered to absorb the remaining itraconazole in the stomach. In severe cases, gastric lavage may be performed to remove the toxin from the stomach. Supportive care, including oxygen therapy, fluid replacement, and cardiac monitoring, will be provided to manage symptoms and prevent complications.

Medications like antacids or acid reducers may be prescribed to alleviate gastrointestinal symptoms. Liver function will be monitored, and treatment adjusted accordingly, as itraconazole overdose can cause liver damage. It is essential to follow the healthcare provider’s instructions and attend follow-up appointments to ensure a full recovery.

Storing and Disposing of Itraconazole

Store Itradus 200 Mg tablets in a cool, dry place, away from direct sunlight and moisture, to preserve their potency and shelf life. This ensures the medication remains effective and safe for consumption.

Dispose of Itraconazole as follows:

Dispose of expired or unused Itradus 200 Mg tablets through a drug take-back program or by following the instructions provided by your pharmacist or healthcare provider.Do not flush Itraconazole down the toilet or pour it down the drain, as this can contaminate the environment.Keep Itradus 200 Mg tablets in their original packaging and store them out of reach of children and pets to avoid accidental ingestion.

Proper storage and disposal of Itraconazole are crucial to maintaining its efficacy and preventing harm to yourself and the environment. Follow the storage and disposal instructions provided by your healthcare provider or pharmacist to ensure safe and responsible use of this medication.

Frequently Asked Questions

Can Itraconazole Be Used to Treat Viral or Bacterial Infections?

Itraconazole is an antifungal medication that primarily targets fungal cells. It is ineffective against viral or bacterial pathogens and is therefore not typically used to treat viral or bacterial infections.

Is Itraconazole Safe to Use During Pregnancy or Breastfeeding?

Itraconazole use during pregnancy or breastfeeding warrants caution. Limited human data and animal studies suggest potential fetal harm and secretion into breast milk.

Can I Drink Alcohol While Taking Itraconazole?

Avoid consuming alcohol while taking itraconazole, as it may increase the risk of liver damage and interact with the medication’s efficacy, potentially reducing its effectiveness or causing adverse reactions.

How Long Does It Take to See Improvement in Fungal Infections?

Fungal infections typically show improvement within 2-4 weeks of treatment, with full resolution often achieved within 6-12 weeks, depending on the infection’s severity and location.

Can Itraconazole Be Used to Prevent Fungal Infections?

Itraconazole can be used prophylactically to prevent fungal infections, particularly in immunocompromised patients. It is effective against a range of fungi, including Aspergillus, Candida, and Histoplasma.

Conclusion

Itraconazole is effective in treating fungal infections, including nail and hair infections. To use it safely, follow dosage instructions and heed precautions to minimize side effects. In case of overdose, seek immediate medical attention. Proper storage and disposal of the medication are crucial to avoid accidents. Understanding itraconazole‘s uses, risks, and guidelines enables safe and effective treatment of fungal infections.

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